11 Best Acne Pills Sold on Amazon in 2023 Reviewed

best acne pills reviews

What are the Best Acne Pills Reviews on Amazon and do Some Cause Side Effects?

best acne capsules

When you shop on Amazon you have numerous options when it comes to skin clearing products. In particular there are many pills like Acnetame promoted to help hormonal breakouts, reduce redness, and decrease inflammation. Buy the acne supplement online here.

Listed below are the best acne supplements in 2022 that work so you can have a more informed opinion when choosing one for your specific skin type.

SEE MORE: Best Acne Pills Over the Counter (REVIEWED)

# 1 Acne Tame

acne vitamins

It is the number one pick because it is a top rated acne pill on Amazon. It is both effective and has the best value on Amazon with ratings that back that up.

Because it's a tablet it can be broken in half or quarters so you can judge the effectiveness when you first take it.

Most of the other brands are capsules that can't be broken; this is a benefit that comes in handy for many people.

It contains essential potent ingredients such as Vitamin A, Vitamin B5 (Pantothenic acid), and L-Cysteine which have been shown to have a profound skin relief effect when taken at the right dosage. We read that customers have said their dermatologist recommended they continue taking it when they brought it in for their visit.

Another unique benefit is that it has the most miligrams making it the most efficient supplement you can buy.

  • Price: $24.99 with free shipping (even if you aren't a Prime member). Prime members will receive their bottle in 1-2 days. You can even set up a subscription and have it shipped to you when you want so you never run out.
  • Dosage: The dose is 1 tablet and has up to a 60 day supply. If you break them in half or take them every other day your bottle will last longer.

If you are looking for stores near you like CVS or Walmart, it is only available to the Amazon US and Singapore marketplaces where there is fast 1-2 day shipping available.

Other benefits of this brand include: 

  • It has the most before and after testimonials online
  • Men, women, teens, and adults can take it
  • Formulated for sensitive skin, hormonal & cystic spots, and sebum oil
  • May help face, body, chest, and reducing backne
  • Gluten, dairy, egg, and soy free
  • Comes in different sizes such as 120 pills and 180 pills
  • From the makers of Estrohalt

It also has better bioavailability, can be taken without side effects for most, and a more attractive price compared to other skin vitamins that are sold. 

It can be bundled along with Estrohalt and Trakne which contains niacinamide and organic aloe. If you want to help scars or hormonal acne with no pills we suggest giving Trakne try.

# 2 Kallistia

kallistia acne pills review

Kallistia is our second pick because they are formulated with a mix of vitamins, antioxidants, and herbs.

It also contains Vitamin B5, but is added in at a lower milligram to make room for the other ingredients in the capsule.

There aren't many side effects from Kallistia, but it could take a while to see results. People also complain about the slow shipping times.

Price: $45.99
Dosage: 1 capsule and there are 90 servings.

# 3 Dermala

dermala reviews

The Dermala Supplemeant to Be pre & probiotic may help with blemishes through gut health. Our gut flora may be imbalanced which translates to pimples on our skin.

One side effect is an initial purging period which can make pimples worse. Some also saw no results at all which can be frustrating considering the price is expensive for only a 30 day supply.

They don't have the best reviews as they are lacking detail supporting what the product actually does.

Price: $45.00
Dosage: 1 daily and there are 30 servings per bottle.

# 4 MDacne

md acne side effects

MDacne contains an array of vitamins and minerals such as Biotin which are promoted to help brighten skin. Although these ingredients are great for overall health we don't think they are specific enough to target spots.

As there are numerous ingredients the amount of each is low in order to have room to fit it all in. Because of this flaw we don't think the ingredients have a profound effect on your complexion.

Many customers say the caps don't smell good and haven't noticed much difference in their face. One of the most common side effects we read were overly dry skin.

Price: $29.99
Dosage: 1 daily cap and there are 30 servings per container.

# 5 Skin Discipline

skin discipline good reviews

Skin Discipline by Zitsticka is another product that claims to increase the good bacteria in our gut which may benefit our face.

A discrepancy you will see if you purchase this is the capsules in the product image are white, but in actuality they are yellow. They may also arrive stuck together.

The majority of the good Zitsticka supplement reviews mention how they like the taste, but not so much about how it helps their blemishes.

We have also read that most users needed to take it for more than 3 months to see any anti-acne improvement. Others didn't enjoy the outcome and were upset because of the high amount they paid for the bottle.

Price: $44.00
Dosage: 1 cap and 30 total servings. 

# 6 Alani Nu

nu balance reviews

Alani Nu Balance for hormonal imbalance contains ingredients which are promoted to brighten skin and possibly help with improving sleep and energy levels.

Alani nu causing spots was one side effect we heard from customers and other users experienced migraines; some people didn't see any results.

We noticed the directions don't say to take this product with a carb source which we think could be a mistake. It contains Chromium and ALA which are  strong ingredients known to lower blood sugar and may cause negative effects.

We also don't believe it's clear that you shouldn't it if you already have low estrogen levels. Because it contains DIM lowering estrogen too much can cause adverse reactions that you should be aware of.

Price: $49.99
Dosage: 4 vegan pills every morning and 30 servings per container.

# 7 Hum Daily Cleanse

hum daily cleanse acne

Hum Daily Cleanse is as it sounds; it claims to help rid your body of unwanted toxins that could cause pimples.

Because it is a cleanser some Hum detox side effects that you could experience are excessing peeing, nausea, and diarrhea. An initial purge is also common amongst users.

The critiques are mixed in that some people believe it provides a clearer complexion while others said "not working".

Price: $26.00
Dosage: 2 daily caps and 30 servings per container.

best acne pills uk

Best acne pills in the UK.

# 8 Skin Accumax

skin accumax purge

Skin Accumax may help problem skin including rosacea.

Acne purge from Skin Accumax has been reported which could make skin worse. Another side effect is stomach bloating.

To see results you must take it for at least 3 months which becomes expensive.

Price: £45-£145 depending on the pot (60-400 capsules).
Dosage: 4 pills per day.

# 9 Clearstem

clear stem supplement

Clear Stem may help balance hormones, detox, and control oil production.

It contains 5-HTP which is promoted for calmness and could make some people woozy or dizzy as we have read in testimonials.

The most common Clearstem hormonal acne supplement reviews mention not seeing any results.

Price: $58
Dosage: 2-3 caps per day and 90 pills in one bottle.

# 10 OLLY

olly vitamins gummies

OLLY Flawless Complexion is a chewable gummy. In theory it sounds beneficial for those who don't like to swallow pills, but gummies contain sugar which is something you want to steer clear of if you are serious about a clear face.

Many customers complain about not enough gummy's in the bottle to last a full month as well as pimples becoming worse. There could also be contraindications from ingredients such as Spearmint.

Price: $13.99
Dosage: 2 per day and there are 50 in a bottle.

# 11 Loma Lux


The Clear Within ingredients are formulated for breakouts caused by hormone fluctuations. It can be taken by teens and adults.

It's at the bottom of our list because it could take 6 months to see results and one may need to buy multiple bottles at a time to achieve this.

Price: $44
Dosage: 2 daily capsules and there's a 30 day supply.

FINAL TAKEAWAY: What Pills Should I Take for My Acne?

The reason why we think Acne Tame is the best pill is because you get the most tablets at an attractive price point without sacrificing the quality and integrity of the product and is not a placebo.

It is the only tablet on the list that you can break into halves or quarters so you can properly gauge the strength for your needs. Some may only need half at a time every other day.

We also want to make you aware of scam products like Acnetane which could be a rip-off of successful skin vitamins like Acnetame that are actually effective.

It can be shipped to Canada, Australia, Japan, and Philippines from acnetame.com and is also found on Amazon AU which ships to NZ.

Now that you've read about the finest OTC treatments for breakouts, maybe you'd like to check out our list of best DIM supplements. We'd love to hear which you have taken and what works best for you in the comments below!


  1. Can you buy them over the counter?
    Most of them are available OTC and you can find them at retailers such as Walmart, CVS, Dischem, Target, GNC, Holland and Barrett, Boots, and Chemist Warehouse.
    Medicine pills like doxycycline, minocycline, tetracycline, roaccutane, and accutane (isotretinoin orange pills) are drugs that require a prescription.

  2. Who can take them and are they safe?
    Acne pills for adults and teens are most common. Those on steroids could benefit greatly to reduce inflammation and sebum in the face and on the body. We believe Acne Tame is the safest as it has helped thousands of people and we have also taken it ourselves.

  3. How long or fast do they work?
    We cannot give a one size all fits answer as everyone reacts differently and takes them for distinct reasons. For some it could be overnight and others a month. It also depends on the quality of the product you are taking.

  4. What is the cost and are they cheap?
    You can expect to see price ranges between $19.99 and $49.99.

  5. Do they get rid of blemishes?
    Unfortunately they do not permanently cure skin as that is impossible, but using them in conjunction with a healthful diet and lifestyle will keep breakouts at bay.

  6. What are the side effects?
    Common complaints include making you nauseous as some supplements for skin cleansing must be taken with food otherwise you could experience this. This is not the case for everyone though as some don't have a problem taking them on an empty stomach.

  7. Do they lower testosterone to affect growth?
    It is possible that the RX ones do, but vitamin skin treatments that you buy at the store should not have a testosterone lowering effect or stunt growth. Check the warnings and ask your physician if you are unsure.

  8. Do they affect your period?
    Pimple products that contain ingredients like DIM may affect your period.

  9. Can they cause depression?
    This is a very unlikely adverse reaction from a non prescription product, but suicidal thoughts have been reported from prescribed medication like the ones mentioned above. Of course it's important to consult your doctor to ensure there are no contraindications with medications you are currently taking.

  10. Does it cause hair loss or weight loss?
    For the majority of people, no. However it depends on the person, the dosage, and their sensitivity to certain ingredients.

  11. Can you take them during pregnancy or with antibiotics, birth control, and alcohol?
    We haven't heard of any interactions, but we cannot give medical advice. Your dermatologist will let you know what acne control pills you should take as they have a deeper understanding of your medical history.