Clearstem Acne Supplement Review- Any Side Effects?

clearstem acne supplement review

You can find Clearstem acne supplement reviews online, but DO the ingredients cause side effects in some people?


This product is called the Mindbodyskin hormonal acne supplement and is promoted to help breakouts by targeting oil, detoxing, and balancing hormones to clear from within. It can be taken by females and males who are experiencing these symptoms.

How Long Does it Take for Clear Stem to Work?

The company says to expect results in 7-10 days and also mention certain foods that previously triggered a breakout may not cause a reaction anymore. Don't be fooled into thinking it can override a true issue within.

There are 90 pills in one bottle and the serving size is 3 capsules. It must be taken with a meal and cannot be taken on an empty stomach as we believe people can experience nausea when taking pills without food.

If you are 125 pounds or less you are instructed to start with two capsules.

This is the first skin clearing supplement for acne we have reviewed that contains 5-HTP. Usually this ingredient is found in calming supplements. For this reason, Clear stem skincare suggests taking it in the evening if you feel too relaxed.

Negative Side Effects

The adverse reactions reported are:

  • feeling dizzy or lightheaded
  • breaking out more or skin getting worse
  • nauseousness if taken without enough food
clearstem hormonal acne supplement reviews


The Clearstem hormonal acne supplement may not work for everyone as we've read bad reviews of numerous users not seeing results.

We can understand their frustration considering you're supposed to see benefits quickly. Even after two months some had no luck.

More Clearstem supplements reviews can be found on Reddit and their website, but not on Amazon as it isn't sold there. If you're looking for a good acne supplement for hormonal breakouts on Amazon we think you'll like Acne Tame.

clearstem acne supplement reviews
I think I am going to be starting my third bottle soon and I don't think anything major has happened. Still have angry hormonal acne. Im trying to give it the 3 full months to see if it has any effects. I know the ingredients are great but it doesn't seem to be as effective as advertised. It is also so expensive with no discounts from the company at all, which is very disappointing for a potential product you would buy every month. Even the "subscribe and save" option is the exact same price on their website! And the Black Friday promo is even excluding this product. Just seems unsustainable to ask people to continue to buy a $60 bottle for 1 of the many supplements a person usually buys...

Mind and Body Ingredients

  • 5-HTP

We believe this is the ingredient which can make someone feel woozy. It's main use is to reduce stress and promote a restful night's sleep. Be aware it may have interactions with other sedative medications.

We haven't read any studies about it's effectiveness on blemishes, but as it may lessen sugar cravings it could play a secondary role in reducing the inflammation from foods that cause acne.

5-HTP contains a form of vitamin B6 which increases pimples when overdosed so one may not want to supplement B6 simultaneously.

  • Glutathione

Glutathione aids in detoxification and supports the liver. It is a powerful antioxidant that may brighten skin and reduce the appearance of scarring.

  • Vitamin B5

Pantothenic acid or vitamin B5 has a profound effect on reducing the oil in our skin called sebum. Sebum is important to keep our skin lubricated, but an over production can clog our pores.

  • DIM

Diindolylmethane for acne works well when taken at the right dose and under the right circumstances.

For example; if you are a person with already low estrogen levels you don't want to take DIM because it can cause bad side effects like hair loss, joint pain, and migraines.

Check out our list of the best DIM supplements sold on Amazon.

  • Vitamin A

Vitamin A is a non pore clogging ingredient and has been shown in studies to improve the softening and shedding of the skin surrounding pores. This process helps to lessen the chance of breakouts. 

Vitamin A may also increase cell turnover which supports the faster regeneration of cells and tissues.

  • Dandelion Root

Dandelion root is an herbal ingredient which has been used as a detoxifying agent for centuries.

There aren't studies showing a direct correlation between dandelion root and pimples, but interestingly it increases glutathione which we now know is an antioxidant which helps the skin.

  • Other ingredients

Vitamin b6, vitamin b12, turmeric, protease, betaine hydrochloride, silicon dioxide.

Where to Buy Clearstemskincare

You can find mind body skin on Amazon as well as their website. They often have coupon codes you can use, but there's no discount on that we saw on the subscription page.

The price of one bottle is $58 which we believe is expensive for a 30 day supply. Our recommendation is the Acnetame 30 count for $19.99 which requires one 1 tablet taken daily instead of 3 capsules.

Pros and Cons

What we find helpful is the founders of the company put together a masterclass called Clearstem ingredient checker which gives you knowledge about products that may be suitable for acne as well as skin care tips.


  • Contains some ingredients which help blemishes
  • Suitable for men & women
  • May help digestive issues


  • Expensive for a 30 day supply
  • 3 caps daily
  • Could cause side effects

How Do You Treat Hormonal Acne Naturally?

There are factors that contribute to hormonal acne such as genetics which are hard to control. With the help of acne vitamins, a diet very low in sugar, and a healthful lifestyle you may see relief naturally.

Vitamins for acne are important because they work from the inside out to help you achieve clearer skin. You can feel confident when you take Acnetame because the natural ingredients such as vitamin A, b5, and b3 help cell turnover, lessen sebum production, and decrease redness.

CONCLUSION: Will You See Results from the Clearstem Vitamin?

After reading the clearstem skincare reviews online and doing our own research we think this supplement could be worth a try.

Unfortunately we believe it's too expensive and there are ingredients in the stack which may not have an effect on acne such as 5-HTP and turmeric.

We think you'll like Acne Tame as it's a top rated acne pill on Amazon. Let us know what you think in the comments below.