Calcium D Glucarate Review- Detox Symptoms and Side Effects

calcium d glucarate review

Calcium D-Glucarate by Addrena Supplements has many positive reviews online, but what is this product actually beneficial for and are there side effects?

This product review will tell you all you need to know about Calcium D-Glucarate and how it may help you.

What is Calcium D-Glucarate Used For and How Does It Help Detox Symptoms?

Calcium D-glucarate is the combination of calcium and glucaric acid. Foods including grapefruit, apples, and oranges contain glucaric acid. 

Calcium D Glucarate helps with the detox symptom process within the body. D-glucarate supports Stage II glucuronidation which is a main detoxification pathway that deactivates toxins and boosts their elimination.

It may also provide benefits such as promoting normal cellular function, breast, prostate, and liver health for Gilbert's Syndrome. It provides a vital protective function for our immune system inhibiting the beta-glucuronidase enzyme that may otherwise interfere with the safe elimination of excess estrogen.

This supplement won't make you gain weight as it helps many people with weight and fat loss caused by too much estrogen.

The main health benefits come from the d-glucarate and not the calcium. If you are looking for a calcium source it would be better to supplement with calcium citrate or calcium carbonate.

Benefits of Calcium D Glucarate

  • May help clear acne
  • Bloat reduction
  • Weight loss (reddit talks about this)
  • Reduce inflammation
  • Increase energy
  • Better digestion
  • Eases anxiety
  • Improves mood & sleep
  • Appetite control
  • Improves hair loss
  • Helps hot flashes
  • Decreases LDL cholesterol

Mechanism of Action

Normally the liver goes through what is called “phase II detoxification” which transfers glucuronic acid to potentially harmful hormones. This process allows for elimination of these toxins and hormones through urine and bile.

Beta-glucuronidase is an enzyme that is naturally present in the body and helps to break up xenobiotics and steroid hormones. This allows them to become “free” and recirculate in the body.

The body can normally have a balance between the two, but in some circumstances if beta-glucuronidase are increased it can lead to an increase in xenobiotics and steroid hormones.

Calcium D-Glucarate can help maintain balance of this enzyme which promotes a healthy elimination of hormones and toxins. (1)

calcium d glucarate detox

Who is Likely to Take Cal D G?

Both men and women suffering from estrogen dominance could benefit greatly from Calcium D-Glucarate. Estrogen dominance occurs when the body has a circulation of too much estrogen.

Side effects of estrogen dominance include acne and skin problems, abdominal fat, excessive sweating, water weight, gynecomastia (enlargement of breast tissue in men), PCOS, and anxiety. Calcium d glucarate could help with these issues.

Calcium d glucarate for hair loss is another reason why people take it and could also be contributed to a hormonal imbalance.

If you experience any of these symptoms and need a detox of your body then Calcium D-Glucarate could be a good supplement for you.

Advserse Side Effects and Detox Symptoms

A change in urine color commonly occurs when you first start detoxing. It is one of the normal calcium d-glucarate side effects and will dissipate after continued use of the supplement.

Some other calcium d glucarate detox symptoms are headaches. Not all users report headaches, but they can be common within the first 1-2 weeks as it is part of the detoxification process. After continued use the headaches will go away. If you previously suffered with headaches you may notice that Cal D-G can relieve them.

Diarrhea may be a detox symptom, but is not very common. If this negative side effect occurs it is likely your dose is too high. In fact, if your digestion is out of whack it could mean your estrogen is high and you will benefit from taking Calcium D-Glucarate.

Can I Drink Alcohol With This Supplement?

As alcohol is a diuretic is can effect how fast calcium d-glucarate is flushed out of the body therefore decreasing the effectiveness. It is not recommended to drink alcohol and take cal d g for this reason as you would be negating the positive effects.

Is Calcium D Glucarate Dangerous?

There isn’t much evidence showing that calcium d glucarate is dangerous and we haven’t heard of any severe side effects.

With that being said, it is important to speak with your doctor about any potential interactions with other prescriptions/drugs that you may be taking.

Where Can You Buy It?

Calcium D-Glucarate can be purchased on Walmart and on Amazon in multiple marketplaces including United States, UK, DE, FR, IT, ES, and Australia.

Addrena Supplements brand also sells a double pack which is 120 pills instead of 60.

If you are a Prime member on Amazon in any of these countries you will receive free two-day shipping on your order. 

When you purchase calcium d-glucarate from Addrena on Amazon you are eligible for a free bottle. Simply email them with your order # and your experience with the supplement. Their company answers emails within 24 hours, most times even sooner.

calcium d glucarate detox

Cal D-G Amazon Reviews

Calcium D Glucarate reviews are excellent on Amazon with a 4.9 out of 5 star rating at the writing of this product review. You can also find reviews on Reddit.

Customers praise this product for it’s ability to clear skin, relieve back pain and muscle aches, relieve headaches, improve digestion, and improve sleep.

Some reviews also mention how calcium d glucarate has contributed to their weight loss since they have decreased appetite and are eating less.

Some of these customers also take Estrohalt along with Cal D G for increase detoxing effects. You can also buy Estrohalt in the UK from Amazon.

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Verified Purchase

I used this in conjunction with diindolymethane for oestrogen dominance. Within a couple of days i started to feel a lot better.
Less headaches, digestion better, sleeping much better. I stopped after a month and all the problems came back so i am going to
restart and stay on them this time.

I would recommend this product for anyone needing to detox hormones.

What Dose Should You Try and How Long Should You Take Calcium D Glucarate?

The dosage of Addrena's calcium d glucarate depends upon the person. Most people only need one tablet whereas others may need more depending on their size, gender, and specific reason they are taking it.

Other forms of calcium d-glucarate include pure encapsulations like veggie caps and liquid as well. We think it would be hard to judge the strength when taking capsules as you can't break them in half if you felt the dose was too strong at first.

DIM and Calcium D Glucarate

Can you take DIM and Calcium D-Glucarate together? These two supplements go hand in hand among people who want a dual detox of excess estrogen. If you want a bulletproof approach to reducing estrogen these two supplements can be that protection you are looking for.

Both Diindolylmethane & Calcium D Glucarate are naturally found in cruciferous vegetables such as broccoli and cauliflower which are known to support estrogen detoxification and hormonal balance.

Estrohalt is a DIM supplement also sold by Addrena that has great reviews on Amazon and many customers say they take it along with Calcium D-Glucarate for enhanced results.

DIM and calcium d-glucarate side effects may only occur if you already have low estrogen and therefore should not be taken.

Can Calcium D Glucarate Lower Estrogen Too Much?

If your dose is too high it is possible that Calcium D-Glucarate can lower your estrogen levels too much. If you are taking it along with DIM then you run a higher risk of estrogen levels dropping too low as DIM is very powerful in this regard.

Liver Detox & Cancer Prevention

Cal D-G's ability to detox the liver may aid in preventing certain types of cancer such as breast, prostate, and colon. These cancers are dependent on estrogen so eliminating excess estrogen may help the body defend against them.

Detoxifying the liver in general will remove toxins that may build up in the body and cause a multitude of problems.

A 2002 study found calcium d-glucarate stops the production of an enzyme called beta-glucuronidase which is associated with an increased opportunity for various cancers to arise. (2).

There is also a study showing that calcium d-glucarate may help lung cancer. (3)

Moreover, CG may prevent lung cancer in tobacco smokers and ex-smokers by enhancing apoptosis and suppressing the acute inflammation and proliferation induced by tobacco-related carcinogens. CG supplementation has the potential to reduce the risk of lung cancer development in high-risk individuals.

Does Calcium D Glucarate Affect Thyroid?

Excess estrogen may cause hypothyroidism (the slowing of your thyroid) and calcium d-glucarate can help rev it up naturally by detoxing your body.

Regular calcium supplements may interfere with thyroid function, but since the benefits come from the d-glucarate part it is actually beneficial for your thyroid. 

Calcium D-Glucarate weight loss reviews can be found online because an increase in thyroid output can boost metabolism slightly.

Effects on Fertility & Infertility

Infertility in men and women can be caused by environment toxins and hormone imbalances. 

Calcium d-glucarate in women helps maintain a healthy balance of progesterone and estrogen which may increase pregnancy chances.

In men it helps relieve estrogen dominance which is a main cause of infertility.

Is Calcium D Glucarate Safe During Pregnancy?

Not enough information has been found as to whether or not it is safe to take while pregnant. It is best to consult your doctor before taking any supplement if you are pregnant. 

Leaky Gut and Calcium D-Glucarate

There is research that confirms there is a connection between the gut microbiome and estrogen levels within the body. (4) The gut microbiome regulates estrogen through the β-glucuronidase enzyme. When this process is impaired the circulation of estrogen decreases which causes problems throughout the body.

Supplementing with calcium d-glucarate will help the recirculation and detoxification of estrogen and decrease symptoms associated with high estrogen levels.

CONCLUSION: Does Addrena Have The Best Calcium D-Glucarate?

If you are looking for the best calcium d-glucarate we recommend it from Addrena as they are a reliable and trustworthy brand who has been selling supplements for over 10 years.

Your designs for health start with what you put in your body. Addrena is committed to formulating the best products with effective ingredients.

Calcium D-Glucarate has so many beneficial properties to help with your estrogen detox and overall detoxification of your body. We recommend you give it a try.