Actimine Review- Does it Cause Side Effects? UPDATED 2022

acnetime review

Actimine reviews can be found on the web, but does it really work?

The Actimine acne treatment is a daily supplement sold by the company Progressive Health.

I bought my bottle of Actimine from Amazon as they do not accept returns if you purchase it online from Progressive Health. In order to receive a refund you have to return the product without it being used as stated in their return policy. I did not need to contact the company, but you can do so through their site.

When companies don’t stand by their product and offer a true money back guarantee that means that they don’t trust their product so why should we?

Actimine Dosage

The serving size is 3 capsules and there are 30 servings per container.

My first impression of the Actimine acne treatment capsules were that they were on the larger side which may be a problem for some people especially because the dose is 3 capsules daily. Compared to a dime they are much bigger.

actimine for acne
actimine - get clear skin

The capsules are white in color with tiny black spots which I believe is the ingredient MSM because it is a form of sulfur which is black.

I started taking the Actimine acne treatment when my face was a bit oilier than usual as I read in other customer reviews that it had helped their skin. I took the three capsule dose for two weeks and noticed a small improvement in oily skin, but not a huge improvement. I did not see a difference in the redness of blemishes either.

Some customers said that it took about two weeks for the effects to kick in, but they did not say what results in specific started to occur within that time. I guess it depends on the type of skin issue you are trying to fix whether it is oily skin or increased breakouts. If you take care of the oily skin it can fix both problems.

The Actimine acne treatment may help with overall skin care over a long period of time, but it will not give you results right away and it is not a cure for acne or oily skin.

Actimine Amazon Reviews - What Do Other Customers Have to Say?

The Actimine reviews on Amazon are mixed. Some people say they really like it while others did not notice a difference. Others were upset that they increased the price and have now switched to other products.

Most of the latest reviews are from women who are very much into skincare and want to find something to add to their beauty routine to keep acne away.

The Amazon listing has a star rating of 3.7 out of 5 stars.

Most Helpful Actimine Review

Seems to help with excess oil production. Takes about 2 weeks to kick in. Still looking for that Miracle in a Bottle. Please let me know if someone stumbles across it.

Cathy A. Harvey 
"Seems to Help"

Most Critical Actimine Review

not sure yet...going to give it another month might be helping with acne....smells funny, but that makes me think it has something special, that's working...I'm 74 but extremely youthful, and have been battling what I think is hormonal acne for 3 years...everything that helps with the acne dries my skin, and or makes my hair fall out, so, have to walk a tight line. So far, the things that are helping the most seem to be Retin A, Dapsone, vitamin C serum and now, Actimine..

"Smells funny, but that makes me think it has something..."

Actimine Ingredients

These are the ingredients in Actimine:

Vitamin A


Vitamin E


Methylsulfonyl Methane

Gum Guggul Ext

5000 IU

50 mcg

200 IU

10 mg

1500 mg

50 mg

Vitamin A- 5000 IU

Vitamin A is added into this stack at a high yet effective dose for treating acne.  This amount is about as high as you would want to take in a supplement as vitamin A is a fat-soluble vitamin which gets stored in fat cells and is not as quickly excreted from the body as water-soluble vitamins.

Vitamin A in high doses can cause toxicity, but you would have to take around 100,00 IU a day for months in order for that to happen. 

There are different types of vitamin A, and the type that is added into the Actimine skin care supplement is from a form of algae that creates carotenoids to protect the skin. Carotenoids are the pigments that give vegetables their colors, specifically red and orange vegetables. Carotenoids contain phytonutrients and have antioxidant properties which help reduce inflammation among other numerous health benefits.

The reason why vitamin A is beneficial for skin health is because it helps smoothen out fine lines, increases collagen production and unclogs pores.

Selenium - 50 MCG

Selenium is an antioxidant that benefits our skin because it helps protect against free radicals which are chemicals or any "foreign invader" that can damage our skin cells. This includes environmental factors, sun exposure or cigarette smoke.

More specifically for acne, selenium's antioxidant effects have been proven to decrease inflammation that contributes to breakouts as well as overall inflammation in the body.

Vitamin E - 200 IU

Vitamin E is another antioxidant which can help reduce inflammatory acne and slow the signs of aging because it helps smoothen out skin.

This vitamin is popular for reducing the appearance of acne scars when applied topically to the skin as it is easily absorbable.

Zinc - 10 mg

Zinc is a mineral that we take when we are sick because it helps boost our immune system. and reduces inflammation. Our immune system plays a role in the development of acne as a weakened system is less likely to be able to fight off pimple causing bacteria.

Zinc, especially in men, can increase testosterone which is the androgen that causes acne. The dose of 10 mg is low enough that it should not affect testosterone or increase breakouts.

Methylsulfonyl Methane - 1500 mg

Methylsulfonyl Methane (MSM) is a natural form of sulfur and is found naturally in the human body. Sulfur is a powerful detoxifier, reduces inflammation, and is also one of the most important antioxidants that our bodies produce as it increases the effectiveness of other antioxidants in our body.

MSM may be helpful for other skin issues as well other than pimples. A study showed that MSM may help symptoms of rosacea which is an inflammatory skin disorder that is characterized by a flushing of the cheeks, nose, and chin as well as tiny pimple-like bumps.

Gum Guggul Extract - 50 mg

Guggul is the sap that is formed from the guggul tree which is most commonly found in India. It has been used in Ayurvedic medicine as it has anti-bacterial properties, aids in detoxification of the body, and supports the immune system (1).

Many times breakouts can be caused from inflammation within the body which is why guggul may help reduce breakouts as it is known to have anti-inflammatory effects.

One study showed that patients who took guggul had about the same reduction in acne as the prescription antibiotic Tetracycline. It also showed that people who had more oily skin actually responded better to guggul. (2)

Guggul is also used to help support our thyroid which helps balance our metabolism. Pimples may actually be an indicator of our thyroid being too slow.

Other ingredients: vegetarian capsule (hypromellose), rice powder, magnesium stearate.
These ingredients are fillers that help make up the capsules and makes the pill easier to swallow as well.

Where Can You Buy Actimine?

The Actimine supplement is sold on the Progressive Health website and can be shipped outside the US to countries like the UK, South Africa, Philippines, and Australia. If you live in the US you can also buy it from Amazon. Actimine is not for sale in stores like Walmart.

The Actimine price on Amazon is $59.95 plus free shipping if you are Prime member. It is the same price on the Progressive Health website, but shipping is not free.

Actimine Side Effects

Although rare, these are some possible side effects from ingredient interactions with other drugs.

Vitamin A

May increase bleeding when taken with other drugs that increase the risk of bleeding like blood thinners. (3)


May slow blood clotting so taking it along with medications that slow blood clotting may increase chances of bruising. (4)

Vitamin E

May increase effectiveness of Cyclosporine (immunosuppressant) therefore increasing the side effects of the drug. (5)


Some side effects of zinc include diarrhea, nausea, and metallic taste. (6)


Common side effects of MSM include stomach discomfort, diarrhea, and nausea. It is not recommended to take MSM if you are pregnant or nursing as there is a lack of scientific evidence showing any interactions.

Gum Guggul Extract

The most common side effects of guggul is digestive issues.

It should not be taken with birth control pills as guggul in high doses has been shown to increase estrogen and may interfere with these medications.


Always read labels, warnings and directions for any product including this one to avoid any possible side effects or problems.

Givenchy Acti'mine

This product is completely different from the supplement Actimine as it is a makeup product, but some people especially women may be interested in it for their skin care regimen. It is a correcting primer that you can use as a base that mixes with foundation or moisturizing cream.

It comes in different shades which is designed to tone and correct your skin. It will give your skin a radiant and perfect finished look. You can find and learn more about Givenchy Acti'mine online. You can also shop for it in stores.


Now you have the facts about Actimine to make a decision about whether or not these pills may help you.

Actimine for acne may be beneficial, but from my experience I only noticed a small change. It may help with the overall health of the skin, but may not be specifically targeted towards acne.

If you like this review, you can check out a similar one written about Praventac.

Have you had success with the Actimine supplement? Let us know in the comment section below!