Acnepril Review- Does it Cause Side Effects? UPDATED 2023

Acnepril reviews can be found on the web, but does it really work?

Certain foods, working every day, and even life in general can get in the way of our skin health if we are not careful.

It is important that we include supplements into our routines to help the healing of our skin, but does this brand actually make a product to help get rid of blemishes fast?

Read more about what you should know about the Acnepril acne treatment pills.

oily skin pills

How Acnepril Works

Acnepril acne treatment pills contain ingredients which are supposed to help acne by strengthening the skin with vitamins and nutrients, balancing hormones in the body and detoxifying the skin.

  • Balances hormone levels in the body.
  • Detoxifies the body and skin.
  • Strengthens skin with essential nutrients.

The company doesn't market this product for treating scars, but over time it may help reduce the appearance of a scar because of it's antioxidant properties.

Does Acnepril Work? My Acnepril Results

There are no Acnepril tablets for acne as they only come in capsule form. Personally I do not think the capsules are too big as I take many supplements every day and I am used to swallowing pills, but I have read other Acnepril customer reviews on Amazon who have said that they think the pills are on the bigger side.

They are gelatin capsules and the powder inside is light brown in color. The capsules do not have much of a smell and I do not taste anything when I swallow them. The quality of the product is not bad as I did not have any indigestion after taking it which may happen sometimes when supplements aren't properly made.

Some other Acnepril complaints other than pill size are that the capsules are not vegan because they are made with gelatin.

How to Use Acnepril

The Acnepril directions say to take 2 pills twice daily with meals and plenty of water.

My first day taking this treatment pill I had no visible breakouts, but I did have a tiny bump underneath my hairline at the top of my forehead. I was previously taking 1 tablet of another acne supplement once a day, but had not taken it the day I started Acnepril. Good results with acne pills come from a healthy diet and proper hygiene which can also internally lead to clear skin.

acnepril does it work

The following day I noticed that the tiny bump under my hairline had disappeared, but then I started to develop another small bump in my hair line underneath my temple. This may have been because I had switched acne supplements and it contained different ingredients that Acnepril. Hair loss may occur when you switch supplements depending on the amount of mg of each ingredient in the stack, but I did not experience that.

The night of the second day taking the supplement I started to develop a pimple right in between my eyes. This breakout may be contributed to the use of the product or discontinuation of the previous acne pills.

The power of this supplement is in question as when I took it I experienced more pimples.

Are there any tips I should know while using Acnepril?

Both men and women with combination skin can take this product and can also use topical treatments like benzoyl peroxide cream and aloe vera extract which may help blackheads and whiteheads as well.

 Use a cleansing beauty brush with soft bristles when you wash your face. Benzoyl peroxide face washes are also available to help breakouts.

Moisturizing creams may not be a good idea to use as some contain fragrance which has negative side effects on sensitive skin and may clog pores as well.

Are the Acnepril Reviews Good?

There are over 200 Acnepril pills reviews on Amazon with an overall rating of 3 stars

The top reviews about Acnepril are all "Verified Purchases" which means that the customer actually bought the product from Amazon before writing a review. An unverified review isn't necessarily someone who purchased the product from Amazon so their review does not carry as much weight and you can not be sure if they really bought the product.

Some of the real reviews for Acnepril are bad and some are good as the users explain their positive experiences and side effects.

oily skin pills

The 4 star and above Acnepril acne treatment reviews are pretty articulate in that they explain how long they took the acne pills for, how many weeks or months it took for them to experience any results, if they were taking any prescribed medication or other over the counter products, as well as their age and demographic.

The 1 and 2 star reviewers cut right to the point and said that the product did not work for them at all.

"didnt work for me at all...It made it worse for some reason. I don't even have terrible acne and it didnt help."
-Sapphirah (Amazon Customer)

The two reviews on Acnepril below are the most helpful and most critical customer testimonials.

acnepril reviews
acnepril review

Acnepril negative reviews and positive reviews may help you determine if this supplement is right is for you. You can view more Acnepril testimonials on Yahoo answers and YouTube.

According to, Acnepril scores well meaning that the reviews are mostly authentic and can be trusted.

This is actually a good score compared to other brands.

Acnepril Before and After Images

We do not add in Acnepril before and after pictures into this review because it can be hard to tell what is always real on the internet. In fact, companies such as Facebook ban them from showing them in advertising on their website.

For this reason our website does not partake in showing these images.

Does Acnepril Have Side Effects?

  • Increased acne
  • Diuretic Effect
  • Lack of information about how ingredients react with each other.

The only side effects that I experienced from the Acnepril dosage was a breakout that I didn't have before I started taking the pills. There could be other factors that played into getting a pimple like sleep, hormones, and lifestyle, but before I started taking the supplement my skin was clear and after I started taking it I broke out so to me there seems to be a correlation.

Other customers have also experienced more zits when they started to take these pills as well as increased pore size from Acnepril. Weight gain should not be an issue with these pills as it may have a slight diuretic effect on some people which will help drop water weight.

All of the ingredients are added in at safe or low levels so this product shouldn't give you any serious side effects.

Because this supplement contains 19 different ingredients and we do not know how these substances react with each other, this is an unknown and something we should be cautious with.

Problems and Warnings

Check with your doctor if you experience any of these common side effects or problems including mild diarrhea, nausea, or upset stomach.

If you experience any severe side effects or problems including hives, itching, difficulty breathing, or numbness and tingling of the skin seek medical attention immediately.

What are the Acnepril Ingredients?

The Acnepril label show many different ingredients. Overall there are 19 Acnepril active ingredients in this stack for treating acne. You can see a list of them below.

There are a few main ingredients in the Acnepril acne treatment including Vitamin A, Biotin, Vitamin B5, and MSM which have benefits for helping breakouts, but the other ingredients in my opinion are more beneficial for overall health and are not designed specifically for acne or clear skin.

You will only find in depth information about 9 of the 19  Acnepril ingredients on their website.

acnepril ingredients

Vitamin A

250 IU

Vitamin C

30 mg


500 mcg

Vitamin B5

210 mg


17.5 mg

Green Tea, DMAE, ALA

Proprietary blend


135 mg

Dandelion Root

110 mg

Witch Hazel

110 mg

Apple Cider Vinegar

100 mg

Licorice Root

100 mg


100 mg

Glucosamine Sulfate

85 mg

Milk Thistle Seed

75 mg

White Willow Bark

75 mg


60 mg

Noni Fruit

35 mg

Vitamin A is an acne vitamin that is used in many skin care product as it is a form of Retinol which mainly helps wrinkles and early signs of aging.

You may have heard of Retinol and retinoids which are both a form of Vitamin A, but are different in that Retinol is used in over the counter products while retinoids are found in prescription medications.

Amount per serving: 250 IU

According to the Food and Nutrition Board of the National Academy of Sciences the upper limit of Vitamin A intake is 10,000 IU per day. Although Vitamin A is needed for healthy skin high doses of it can be toxic because it is a fat-soluble vitamin (gets stored in fat in the body rather than being excreted in the urine like water-soluble vitamins).

I think that the dosage is a bit low for proper skin health and they probably could have added more by taking out a less effective ingredient from the stack.

Vitamin C is a powerful antioxidant which is beneficial for our skin in that it helps skin elasticity and lightens dark age spots. A strong immune system is imperative for clear skin and Vitamin C is a known immune boosting vitamin.

Amount per serving: 30mg

The recommended amount of Vitamin C per day is 65-90mg. Vitamin C is a water-soluble vitamin so more than this recommended amount is not technically harmful, but large amounts of this vitamin may cause diarrhea and nausea.

The amount in this product may be too low for receiving the antioxidant effects of Vitamin C, but it also depends on how much you are already receiving through food and other supplements as well.

Biotin is a water-soluble vitamin that helps to create a protective barrier around our skin which may help smoothen out complexion. Biotin also helps our nails and hair grow faster.

Amount per serving: 500mcg

The recommended daily serving of Biotin 2500mcg. Again, this is on the low side but there are a few number of people who may react negatively to Biotin in that they get the opposite effect including more breakouts and hair loss.

Vitamin B5 (Pantothenic Acid) at high doses has been shown to reduce the production of sebum (oil) from our skin which contributes to oily skin. It does so by increasing a compound called Coenzyme A (Co-A) which as described by Dr. Jeffery Dach "increases the metabolic breakdown of oils in the skin as they are oxidized and used as energy." (1)

Amount per serving: 210mg

Calcium may help overall skin health as it may help the growth of new skin cells along with being beneficial for joint and bone health.

Calcium also has an alkaline effect on the body which may help to balance our pH levels which are an important factor in skin health.

A deficiency in calcium also causes white spots to appear on the skin (also known as calcium deposits).

Amount per serving: 17.5mg

Proprietary blend

The next 3 Acnepril ingredients are part of a propriety antioxidant blend. The amount per serving in total is 175mg. A proprietary blend is a company's own specific formulation of ingredients. You are aware of the ingredients in the product, but are not given the exact mg of each ingredient.

Green tea contains a potent antioxidant in EGCG (epigallocatechin-3-gallate) which may help reduce inflammation and early signs of aging.

A study was done showing that EGCG also has anti-carcinogenic effects as using it topically as well as drinking green tea helped to reduce the damage caused by UVB rays. (2)

Dimethylaminoethanol or DMAE is most commonly used in nootropic supplements as it is a precursor to choline and acetylcholine which are neurotransmitters in the brain that control our mood, energy, and cognitive function.

The way it helps skin is by improving its texture and also enhances the effectiveness of antioxidants like Alpha Lipoic Acid and Vitamin C.

ALA like DMAE helps to increase the effectiveness of other antioxidants which may help smooth wrinkles. It may also help with inflammation and protecting against damage from free radicals.

MSM helps to increase regeneration of skin cells and is a compound of sulfur. Sulfur has been used for thousands of years to help combat skin issues like acne, psoriasis and eczema.

Amount per serving: 135mg

The amount of MSM that people usually take depends on the issue that they are trying to correct as MSM is not only good for skin but also good for metabolism, bone and joint health, and increasing blood circulation. For example, people with osteoarthritis take 500mg 3 times a day. (3)

High doses of of MSM have not been shown to be harmful, so it depends on the severity of your acne and other conditions to determine how much is right for you specifically. The higher the serving the better, most likely.

Dandelion Root is a potent diuretic which helps to flush excess water out of our bodies. This is helpful for skin in that it may help remove unwanted toxins that may build up in our skin and cause clogged pores which lead to pimples.

Amount per serving: 110mg

Dandelion root is ingested mostly through tea or by supplement form if digestive issues occur. The amount per serving in supplement form is usually between 500 and 540mg.

This supplement is not marketed as a diuretic so the amount per serving does not have to be so high.

Witch Hazel is a natural astringent which may help dry our pores and reduce inflammation because of the high amount of tannins contained in it.

Most Witch Hazel Leaf supplements are 400mg but they are not marketed specifically for acne as they are targeted towards people with varicose veins. Most people use Witch Hazel topically for treating skin issues such as pimples and eczema.

Amount per serving: 110mg

It is added to the stack at a low dose which will decrease the amount of side effects that occur when taken taken orally including upset stomach and at high doses liver problems.

ACV is also a natural astringent. It's main purpose for helping skin issues is balancing the pH in our bodies so that we do not become too acidic or too alkaline which is a contributing factor to breakouts.

Amount per serving: 100mg

ACV is usually taken orally in liquid form but it comes in supplement form as well. The mg of Apple Cider Vinegar supplements are usually between 450 and 600. As a secondary ingredient it is added in at a dose where it may provide some effectiveness for acne.

Licorice root has been used for many ailments such as sore throat, stomach ulcers, and heartburn as it enhances immune function. (4)

The role that it plays on skin is that it has anti-inflammatory properties which may help reduce pimples when applied topically and may help rosacea and psoriasis as well.

Amount per serving: 100mg

Licorice root also contains a compound called glabridin which helps lighten skin tone and may help reduce dark age spots when applied topically. Another compound called glycyrrhizin also helps reduce inflammation in the body, but can cause hormonal disruption as it increases cortisol and decreases testosterone. Because of this it is not recommended to take in high doses especially if you are pregnant, have high blood pressure, or diabetes.

150-300mg is the common dose taken that does not provide disruption of hormones. It is added into this stack at a safe dose.

Garlic is a natural antibiotic which is why it is recommended to use when you have a cold or the flu. Garlic can help boost our immune system which in turn helps reduce acne because garlic helps fight bacteria.

Amount per serving: 100mg

Too much garlic does not necessarily hurt you, but it may cause nausea, vomiting, diarrhea, and even body odor that smells like garlic. The dose in Acnepril is a very low amount and will not cause these negative side effects.

Glucasomine sulfate is a compound made in the body which produces glycosaminoglycans in the skin specifically hyaluronic acid. Hyaluronic acid is used in many anti-aging products as it helps to smoothen our wrinkles.

It is also naturally found in our body and provides anti-inflammatory effects for our bones and joints. (5)

Amount per serving: 85mg

Usually people take Glucasomine sulfate at a higher dose of 500-1500mg a day and it also produces results when taken with MSM which is also added into this supplement stack.

Milk thistle is primarily used for detoxing the liver. Our liver is basically our bodies filtration system so keeping our liver functioning properly will only help heal numerous health ailments including acne and other skin issues.

Amount per serving: 75mg

For detoxing the liver and antioxidant effects the recommended dosing is between 140 and 800mg per day.

White willow is an astringent as it contains a natural from of salicylic acid. Salicylic acid is used in acne creams to reduce inflammation, relieve redness, kill bacteria in pimples, and remove dead skin cells. It is also a potent antioxidant in that it contains tannins and flavonoids which are beneficial for our overall health.

Amount per serving: 75mg

The usual dose of White Willow Bark is 240mg. There was a study conducted on people who had neck and back pain and the group that received a high dosage of White Willow Bark at 240mg had less pain than those who who received 120mg. (6)

Higher doses may cause side effects like upset stomach and skin rash when applied topically.

Mangosteen is a fruit that contains antioxidants called xanthones. There are two types of xanthones occuring in this fruit in "alpha mangoseeten and gamma mangosteen. (7)

These xanthones help the skin as they have anti-inflammatory and anti-aging properties to decrease any sign of aging and protect against free radicals which are compounds that attack the healthy cells in our body.

Amount per serving: 60mg

The typical daily dosage of Mangosteen is 500mg twice daily. A dosage of 60mg may be a bit low if you want the antioxidant effects of this ingredient.

Noni fruit is known for its many beneficial health effects as it contains compounds such as polysaccharides, polyphenols, and flavonoids. (8)

It is most commonly sold in juice form, many times with added sugar so it is best to buy unsweetened if you want all of the beneficial effects.

For skin issues specifically it is better to use it topically as it contains antimicrobial, anti-inflammatory, and anti-fungal properties and when taken orally it is more beneficial for stomach issues and candida.

Amount per serving: 35mg

You can take up to 500mg of Noni Fruit daily without any side effects. The mg which works well for skin depends on the person.

acne tame supplement

Acnepril Vs ClearZine

Many people wonder if they should take Acnepril or Clearzine. They both have their pros and cons and it really depends on the person and how severe their breakouts are.

Acnepril gets confused with the Revitol Solution "AcneZine" as well. If you are interested to see if there is a difference between the two, you can read our AcneZine review.

Where to Buy Acnepril

Many people wonder "where is Acnepril for sale?". You can not buy Acnepril over the counter from a market or store like Walmart or CVS, but you can buy it online which is convenient as the store doesn't close!

People also ask if you can purchase the Acnepril acne treatment in a place like South Africa, Kenya, Malaysia, NZ, Philippines, Qatar, UAE, and the UK.

Official Website Information


There is a 100% money back guarantee if you are not satisfied with the product. You can return the supplement within 90 days of purchase for a refund of the cost of the bottle, but the terms include you having to pay shipping to send it back to them.


Cellusyn Labs is the manufacturer of Acnepril which is made in the United States. They also sell and manufacturer a bunch of other products as well including detox, brain, and joint supplements.

If you are wondering "is Acnepril FDA approved?", it is not. Supplements do not need to have approval to be sold.

What is the Ordering Process of the Supplement?

One bottle:

  • Price: $29.99
  • Serving Size: 2 capsules twice daily with 12-16 ounces of water
  • Servings per Container: 60
  • Quantity: 120 Capsules
  • Strength/Effective dose: 1400mg per serving

When I first visited the Acnepril website I clicked on the big red button that says "See Pricing". It brought me to the bottom of the page where you could choose from Starter, Most Popular, or Best Value. The more bottles you buy the better deal on Acnepril you receive.

acnepril bottles


  • 1 bottle of Acnepril (1 month supply)
  • Price: $29.99
  • Shipping: $4.95 Flat-rate

Most Popular:

  • 2 bottles of Acnepril (2 month supply)
  • Price: $59.99
  • Shipping: Free
  • 1 Free Acneeva

Acneeva is the skin care serum that they sell which contains tea tree oil.

Best Value:

  • 3 bottles of Acnepril (3 month supply)
  • Price: $89.99
  • Shipping: Free
  • 3 free Acnevva

Since it was my first time trying it I decided to go with the cheapest option which was one bottle of a one month supply. 

A coupon code for 10% off popped up on my screen that I was able to enter at check-out which took three dollars off of my purchase for this pill for acne. Offer codes are not made readily available by many companies on their website so it was nice to get a slight discount.

You can use your PayPal account to purchase the supplement which will ensure the safety and privacy of your purchase.

acnepril review


On the website it said that shipping is $4.95 and it ships via flat rate. When I purchased my bottle of Acnepril the shipping actually came to $5.95 and it was first class not flat rate. The package was shipped from Utah, United States.

When I received the package it had been opened by the post office or mail carrier as the print on the shipping label was very hard to see and they could not make out my address without opening the package. Accidents do happen and this could happen with any company, but it did delay the delivery of my package.


If you scroll down towards the bottom of the home page you will see a frequently asked questions section. Underneath that is a link to contact their support team. Once you click on that link you can fill out a form to ask a question, but at the bottom of the form is also the address to send your bottle for a refund.

There is also a "Contact Us" tab at the top right of the website so you can email them quickly.

*UPDATE- I was unhappy with the product and sent the bottle back to the company within the allotted time. I did not receive a refund because they said they needed a tracking number for my package to process my return more quickly. I sent out my package via First Class mail as it was the cheapest option for me as I already had paid $5.95 for them to ship the product to me.
If they need a tracking number in order to process a refund they should explain that on their website or provide the customer with return postage.

CONCLUSION: Does Acnepril Work?

Acnepril effects like reducing oil production may be noticeable for some as there are many customers who love the product and feel that they have experienced results from it, but results will vary.

In addition, there are a few good ingredients in this stack that are needed for helping a skin problem such as acne, but since there are many ingredients in this product there is a higher likelihood that a person may react negatively.

If you are using Acnepril for cystic acne you may not see pronounced results so you may not want to add it to your acne fighting arsenal.

This is a "kitchen sink" formula which works well in a marketing process because it sells the idea to the customer that the product is filled with a lot of great ingredients which based on common sense should give excellent results.

Unfortunately the customers needs are not actually met as the focus is on selling the product and not the product actually performing well to clear up and change the appearance of your skin.

acnepril side effects

Could this product help some people? Maybe. But it will not treat chronic breakouts. Don't buy this product if you only have scars as there are other products out there which are specifically formulated for that.

I recommend that before taking this tablet, start to cut our dairy, sugar, and high-glycemic carbs as these foods cause hormonal breakouts.

I would not make it your first option if you are trying to get clear skin. Calling it a scam may be too strong of a word, but I never got a full refund when I sent my bottle back.

Their customer services communication is questionable and we would warn you to beware of losing your money, not getting results, and not having a good overall experience with this company like we did. I will not buy from this company in the future.

What has worked best to help you with your acne? Please leave a comment below and let us know!










The content on this site is intended for entertainment purposes only. We recommend consulting a medical doctor before starting any supplement regimen. The advice given is based on our personal experience. Please do not use this information to treat, prevent, or cure any disease or condition.